Le système eau-pyroglutamate de zinc : déshydratation et réhydratation des composés de coordination

The relative stabilities of the (S-S) and (R-R, S-S) diaquabis(pyroglutamato)zinc(II) phases, both derived from density and solubility data, and thermal behaviour under pressure, are discussed. These phases dehydrate into amorphous and crystalline anhydrous phases upon heating, which rehydrate at room temperature under saturating water vapour through mechanisms that depend on crystallinity and presumably on diastereo-isomerism

Quantifying widespread aqueous surface weathering on Mars: The plateaus south of Coprates Chasma

International audienc

Evaluation of combustion AMS “MICADAS” for ADME studies

Today, combustion AMS (accelerator mass spectrometry) technology, such as "MICADAS", is considered to enable completion of the human ADME study much earlier and, as a consequence, might represent an opportunity to change the current drug development paradigm. To evaluate the applicability of this method, we successfully performed: a) the validation of MICADAS for radioactivity quantification in biomatrices and, b) a rat ADME study of Leniolisib (CDZ173), where conventional methodology was assessed against a microtracer and “MICADAS” approach

Refining the age, emplacement and alteration scenarios of the olivine-rich unit in the Nili Fossae region, Mars

International audienc

MarsSI: Martian surface data processing information system

International audienceMarsSI (Acronym for Mars System of Information, https://emars.univ-lyon1.fr/MarsSI/) is a web Geographic Information System application which helps managing and processing martian orbital data. The MarsSI facility is part of the web portal called PSUP (Planetary SUrface Portal) developed by the Observatories of Paris Sud (OSUPS) and Lyon (OSUL) to provide users with efficient and easy access to data products dedicated to the martian surface. The portal proposes 1) the management and processing of data thanks to MarsSI and 2) the visualization and merging of high level (imagery, spectral, and topographic) products and catalogs via a web-based user interface (MarsVisu). The portal PSUP as well as the facility MarsVisu is detailed in a companion paper (Poulet et al., 2018). The purpose of this paper is to describe the facility MarsSI. From this application, users are able to easily and rapidly select observations, process raw data via automatic pipelines, and get back final products which can be visualized under Geographic Information Systems. Moreover, MarsSI also contains an automatic stereo-restitution pipeline in order to produce Digital Terrain Models (DTM) on demand from HiRISE (High Resolution Imaging Science Experiment) or CTX (Context Camera) pair-images. This application is funded by the European Union's Seventh Framework Programme (FP7/2007–2013) (ERC project eMars, No. 280168) and has been developed in the scope of Mars, but the design is applicable to any other planetary body of the solar system